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Design, synthesis and HIV-RT inhibitory activity of novel thiazolidin-4-one derivatives

Hua CHEN, Zaihong GUO, Qingmei YIN, Xiaoxu DUAN, Yunjing GU, Xiaoliu LI

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 2,   Pages 231-237 doi: 10.1007/s11705-010-1022-7

Abstract: A series of 2-aryl-3-(4,5,6-trimethylpyrimidin-2-yl) thiazolidin-4-ones ( – ) and their derivatives bearinga lipophilic substituent, like acetoxy group ( – ), propionyloxy group ( – ), methyl ( and ) at C-5on thiazolidin-4-one ring were designed, synthesized and evaluated for their HIV-RT inhibitory activityshowed moderate HIV-RT inhibitory activity and compounds and with methyl at C-5 showed a weak HIV-RTStructure activity relationship analysis suggested that the substituted groups on C-5 would be unfavorable

Keywords： 5-subsituted thiazolidin-4-ones     Pummerer reaction     anti-HIV-RT activity     SARs    

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Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones

Hua CHEN, Yanan LI, Jie BAI, Lian ZHAO, Xiangguo YUAN, Xiaoliu LI, Keqiang CAO

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 2,   Pages 186-191 doi: 10.1007/s11705-009-0004-0

Abstract: 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones and were synthesized in 41%-67% yield by

Keywords： microwave-assisted synthesis     naphthyl     thiazolidin-4-one     antimicrobial    

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Dechlorination of 2,2′,4,4′,5,5′-hexachlorobiphenyl by thermal reaction with activated carbon-supported

Yifei SUN, Xin FU, Wei QIAO, Wei WANG, Tianle ZHU, Xinghua LI

Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 6,   Pages 827-832 doi: 10.1007/s11783-013-0543-y

Abstract: When applied to decompose 2,2′,4,4′,5,5′-hexachlorobiphenyl at 250 °C, IRCu-C achieved higher activity

Keywords： polychlorinated biphenyls     activated carbon-supported copper or zinc     dechlorination     electron donor    

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5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interactionwith eukaryotic initiation factor 4A-I

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 476-492 doi: 10.1007/s11684-022-0966-6

Abstract: In HCC cells, 5′-tiRNA-Gln overexpression impaired the proliferation, migration, and invasion in vitro and in vivo, while 5′-tiRNA-Gln knockdown yielded opposite results. 5′-tiRNA-Gln exertedits function by binding eukaryotic initiation factor 4A-I (EIF4A1), which unwinds complex RNA secondaryG-quadruplex structure is crucial for 5′-tiRNA-Gln to strongly bind EIF4A1 and repress translation.Collectively, these findings reveal that 5′-tiRNA-Gln interacts with EIF4A1 to reduce related mRNA binding

Keywords： EIF4A1     G-quadruplex     hepatocellular carcinoma     tRNA-derived small RNA     translation initiation    

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On the monolayer dispersion behavior of Co3O4 on HZSM-5 support: designing applicable

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11,   Pages 1741-1754 doi: 10.1007/s11705-023-2332-x

Abstract: Based on monolayer dispersion theory, Co3O4/ZSM-5 catalysts with different loadingsCo3O4 can spontaneously disperse on HZSM-5 support with a monolayer dispersionreaction performance. 4% Co3O4/ZSM-5, the catalyst close to the monolayer dispersionIt is proposed the optimal Co3O4/ZSM-5 catalyst can be prepared by loading thecapacity amount of Co3O4 onto HZSM-5 support.

Keywords： Co3O4/ZSM-5     NOx-SCR by NH3     monolayer dispersion    

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Facile controlled synthesis of hierarchically structured mesoporous Li4Ti5O12/C/rGO composites as high-performance

Cehuang FU, Shuiyun SHEN, Ruofei WU, Xiaohui YAN, Guofeng XIA, Junliang ZHANG

Frontiers in Energy 2022, Volume 16, Issue 4,   Pages 607-612 doi: 10.1007/s11708-021-0798-0

Abstract: In this paper, a facile strategy is proposed to controllably synthesize mesoporous Li4Ti5O12/C nanocomposite embedded in graphene matrix as lithium-ion battery anode via theco-assembly of Li4Ti5O12 (LTO) precursor, GO, and phenolic resin.

Keywords： Li4Ti5O12     phenolic-resin-based carbon     mesoporous composite     graphene    

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UI layers merger: merging UI layers via visual learning and boundary prior Research Article

Yunnong CHEN, Yankun ZHEN, Chuning SHI, Jiazhi LI, Liuqing CHEN, Zejian LI, Lingyun SUN, Tingting ZHOU, Yanfang CHANG

Frontiers of Information Technology & Electronic Engineering 2023, Volume 24, Issue 3,   Pages 373-387 doi: 10.1631/FITEE.2200099

Abstract: With the fast-growing graphical user interface (GUI) development workload in the Internet industry, some work attempted to generate maintainable front-end code from GUI screenshots. It can be more suitable for using user interface (UI) design drafts that contain UI metadata. However, fragmented layers inevitably appear in the UI design drafts, which greatly reduces the quality of the generated code. None of the existing automated GUI techniques detects and merges the fragmented layers to improve the accessibility of generated code. In this paper, we propose UI layers merger (UILM), a vision-based method that can automatically detect and merge fragmented layers into UI components. Our UILM contains the merging area detector (MAD) and a layer merging algorithm. The MAD incorporates the boundary prior knowledge to accurately detect the boundaries of UI components. Then, the layer merging algorithm can search for the associated layers within the components' boundaries and merge them into a whole. We present a dynamic data augmentation approach to boost the performance of MAD. We also construct a large-scale UI dataset for training the MAD and testing the performance of UILM. Experimental results show that the proposed method outperforms the best baseline regarding merging area detection and achieves decent layer merging accuracy. A user study on a real application also confirms the effectiveness of our UILM.

Keywords： User interface (UI) to code     UI design lint     UI layer merging     Object detection    

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China in the eyes of news media: a case study under COVID-19 epidemic Research Article

Hong Huang, Zhexue Chen, Xuanhua Shi, Chenxu Wang, Zepeng He, Hai Jin, Mingxin Zhang, Zongya Li,honghuang@hust.edu.cn,chenzhexue@hust.edu.cn,xhshi@hust.edu.cn,wangchenxu@hust.edu.cn,hezepeng@hust.edu.cn,hjin@hust.edu.cn,mingxinzhang@hust.edu.cn,lzy901014@sina.com

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 11,   Pages 1443-1457 doi: 10.1631/FITEE.2000689

Abstract: As one of the early outbreak areas, China attracted the global news media’s attention at the beginning of 2020. During the epidemic period, Chinese people united and actively fought against the epidemic. However, in the eyes of the international public, the situation reported about China is not optimistic. To better understand how the international public portrays China, especially during the epidemic, we present a case study with big data technology. We aim to answer three questions: (1) What has the international media focused on during the period? (2) What is the media’s tone when they report China? (3) What is the media’s attitude when talking about China? In detail, we crawled more than 280 000 pieces of news from 57 mainstream media agencies in 22 countries and made some interesting observations. For example, international media paid more attention to Chinese livelihood during the period. In March and April, “progress of Chinese vaccines,” “specific drugs and treatments,” and “virus outbreak in U.S.” became the media’s most common topics. In terms of news attitude, Cuba, Malaysia, and Venezuela had a positive attitude toward China, while France, Canada, and the United Kingdom had a negative attitude. Our study can help understand China’s image in the eyes of the international media and provide a sound basis for image analysis.

Keywords： 国家形象；新冠肺炎；主题挖掘；实体；新闻立场；情感    

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Metabolic uncoupler, 3,3′,4′,5-tetrachlorosalicylanilide addition for sludge reduction and fouling control

An Ding, Yingxue Zhao, Huu Hao Ngo, Langming Bai, Guibai Li, Heng Liang, Nanqi Ren, Jun Nan

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1275-4

Abstract: We added the metabolic uncoupler 3,3′,4′,5-tetrachlorosalicylanilide (TCS) to the system to deal with

Keywords： Gravity-driven membrane (GDM)     Energy uncoupling     Permeability     Sludge reduction     Membrane fouling     Fouling layer    

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Wideband circular-polarized transmitarray for generating a high-purity vortex beam Correspondence

Liangjie QIU, Xiuping LI, Zihang QI, Wenyu ZHAO, Yuhan HUANG,xpli@bupt.edu.cn

Frontiers of Information Technology & Electronic Engineering 2023, Volume 24, Issue 6,   Pages 927-934 doi: 10.1631/FITEE.2200539

Abstract: In this correspondence, a wideband circular-polarized (CP) transmitarray (TA) in the Ka-band is presented for generating a high-purity vortex beam. The proposed element is composed of two identical combinations separated by an air layer. The subwavelength structure and double-resonance characteristics ensure the stable phase shift of the element within the 1-dB transmission bandwidth of 28.4%. A square aperture TA fed by a horn antenna is fabricated and measured. Owing to the honeycomb arrangement of elements, the mode purity of l​​=​​−1 is >0.93 in a wide band from 28.5 to 38 GHz. The measured peak gain is 22.3 dBic, and the 3-dB axial ratio bandwidth is 27.6%. The performance of the proposed antenna demonstrates its potential for high-capacity wireless communication and high-quality radar imaging.

Keywords： 轨道角动量；涡旋波束；透射阵；宽带；高纯度    

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Development of space-based diffractive telescopes Review Article

Wei Zhao, Xin Wang, Hua Liu, Zi-feng Lu, Zhen-wu Lu,wangxin971241@163.com,liuhua_rain@aliyun.com

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 6,   Pages 809-962 doi: 10.1631/FITEE.1900529

Abstract: formed by fabricating microstructures on the substrates have two important characteristics, ultra-light mass (surface mass density < 0.1 kg/m2) and loose surface shape tolerances (surface accuracy requirements are on the order of magnitude of centimeter). Large-aperture telescopes using a membrane diffractive optical element as the primary lens have , light weight, and low cost at launch. In this paper, the research and development on space-based s are classified and summarized. First, the imaging theory and the configuration of diffractive-optics telescopes are discussed. Then, the developments in s are introduced. Finally, the development prospects for this technology used as a high-resolution space reconnaissance system in the future are summarized, and the critical and relevant work that China should carry out is put forward.

Keywords： 薄膜衍射光学元件；衍射望远系统；超大口径    

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Texture branch network for chronic kidney disease screening based on ultrasound images Research Articles

Peng-yi Hao, Zhen-yu Xu, Shu-yuan Tian, Fu-li Wu, Wei Chen, Jian Wu, Xiao-nan Luo,fuliwu@zjut.edu.cn

Frontiers of Information Technology & Electronic Engineering 2020, Volume 21, Issue 8,   Pages 1119-1266 doi: 10.1631/FITEE.1900210

Abstract: (CKD) is a widespread renal disease throughout the world. Once it develops to the advanced stage, serious complications and high risk of death will follow. Hence, early screening is crucial for the treatment of CKD. Since ultrasonography has no side effects and enables radiologists to dynamically observe the morphology and pathological features of the kidney, it is commonly used for kidney examination. In this study, we propose a novel convolutional neural network (CNN) framework named the to screen CKD based on images. This introduces a texture branch into a typical CNN to extract and optimize texture features. The model can automatically generate texture features and deep features from input images, and use the fused information as the basis of classification. Furthermore, we train the base part of the network by means of , and conduct experiments on a dataset with 226 images. Experimental results demonstrate the effectiveness of the proposed approach, achieving an accuracy of 96.01% and a sensitivity of 99.44%.

Keywords： 慢性肾脏病；超声；纹理分支网络；迁移学习    

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A compact ultra-wideband crossed-dipole antenna for 2G/3G/4G/IMT/5G customer premise equipment applications Correspondences

Jingli GUO, Lun CUI, Ying LIU, Baohua SUN, Xiaofeng LI,guojl@xidian.edu.cn,ID_CLXX@163.com

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 2,   Pages 339-345 doi: 10.1631/FITEE.2000456

Abstract: A compact ultra-wideband crossed-dipole antenna is proposed for 2G/3G/4G/IMT/5G customer premise equipmentFurthermore, a slotted rectangular parasitic patch is added beneath the crossed dipoles to further support a 5G

Keywords： 5G；交叉振子；双极化天线；终端天线；超宽带    

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Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 1,   Pages 80-84 doi: 10.1007/s11705-008-0017-0

Abstract: 2-(5-Amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl thioester(III), an importantintermediate of the fourth generation cephalosporins, was efficiently synthesized by reacting 2-(5-amino

Keywords： 5-Amino-1     2     4-thiadiazol-3-yl     1     2-dichloroethane     important intermediate     2-benzothiazolyl thioester     temperature    

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Effective regeneration of thermally deactivated commercial V-W-Ti catalysts

Xuesong SHANG, Jianrong LI, Xiaowei YU, Jinsheng CHEN, Chi HE

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 1,   Pages 38-46 doi: 10.1007/s11705-011-1167-z

Abstract: An effective method for the regeneration of thermally deactivated commercial monolith SCR catalysts was investigated. Two types of regenerated solutions, namely NH Cl (1 mol/L) and dilute H SO (0.5 mol/L), were employed to treat the used catalyst. The effects of temperature and the regeneration process on the structural and textural properties of the catalysts were determined by X-ray diffraction, scanning electron microscopy, N adsorption/desorption, elemental analysis and Fourier transform infrared spectroscopy. The results suggest that the anatase phase of the used catalyst is maintained after exposure to high temperatures. Some of the catalytic activity was restored after regeneration. The catalyst regenerated by aqueous NH Cl had a higher activity than that of the catalyst treated by dilute H SO . The main reason is that the NH generated from the decomposition of NH Cl at high temperatures can be adsorbed onto the catalyst which promotes the reaction. The aggregated V O were partially re-dispersed during the regeneration process, and the intrinsic oxidation of ammonia with high concentrations of O is a factor that suppresses the catalytic activity.

Keywords： V2O5-WO3/TiO2 catalysts     thermal deactivation     regeneration     NH4Cl     dilute H2SO4 solution    

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Title Author Date Type Operation

Design, synthesis and HIV-RT inhibitory activity of novel thiazolidin-4-one derivatives

Hua CHEN, Zaihong GUO, Qingmei YIN, Xiaoxu DUAN, Yunjing GU, Xiaoliu LI

Journal Article

Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones

Hua CHEN, Yanan LI, Jie BAI, Lian ZHAO, Xiangguo YUAN, Xiaoliu LI, Keqiang CAO

Journal Article

Dechlorination of 2,2′,4,4′,5,5′-hexachlorobiphenyl by thermal reaction with activated carbon-supported

Yifei SUN, Xin FU, Wei QIAO, Wei WANG, Tianle ZHU, Xinghua LI

Journal Article

5′-tiRNA-Gln inhibits hepatocellular carcinoma progression by repressing translation through the interactionwith eukaryotic initiation factor 4A-I

Journal Article

On the monolayer dispersion behavior of Co3O4 on HZSM-5 support: designing applicable

Journal Article

Facile controlled synthesis of hierarchically structured mesoporous Li4Ti5O12/C/rGO composites as high-performance

Cehuang FU, Shuiyun SHEN, Ruofei WU, Xiaohui YAN, Guofeng XIA, Junliang ZHANG

Journal Article

UI layers merger: merging UI layers via visual learning and boundary prior

Yunnong CHEN, Yankun ZHEN, Chuning SHI, Jiazhi LI, Liuqing CHEN, Zejian LI, Lingyun SUN, Tingting ZHOU, Yanfang CHANG

Journal Article

China in the eyes of news media: a case study under COVID-19 epidemic

Hong Huang, Zhexue Chen, Xuanhua Shi, Chenxu Wang, Zepeng He, Hai Jin, Mingxin Zhang, Zongya Li,honghuang@hust.edu.cn,chenzhexue@hust.edu.cn,xhshi@hust.edu.cn,wangchenxu@hust.edu.cn,hezepeng@hust.edu.cn,hjin@hust.edu.cn,mingxinzhang@hust.edu.cn,lzy901014@sina.com

Journal Article

Metabolic uncoupler, 3,3′,4′,5-tetrachlorosalicylanilide addition for sludge reduction and fouling control

An Ding, Yingxue Zhao, Huu Hao Ngo, Langming Bai, Guibai Li, Heng Liang, Nanqi Ren, Jun Nan

Journal Article

Wideband circular-polarized transmitarray for generating a high-purity vortex beam

Liangjie QIU, Xiuping LI, Zihang QI, Wenyu ZHAO, Yuhan HUANG,xpli@bupt.edu.cn

Journal Article

Development of space-based diffractive telescopes

Wei Zhao, Xin Wang, Hua Liu, Zi-feng Lu, Zhen-wu Lu,wangxin971241@163.com,liuhua_rain@aliyun.com

Journal Article

Texture branch network for chronic kidney disease screening based on ultrasound images

Peng-yi Hao, Zhen-yu Xu, Shu-yuan Tian, Fu-li Wu, Wei Chen, Jian Wu, Xiao-nan Luo,fuliwu@zjut.edu.cn

Journal Article

A compact ultra-wideband crossed-dipole antenna for 2G/3G/4G/IMT/5G customer premise equipment applications

Jingli GUO, Lun CUI, Ying LIU, Baohua SUN, Xiaofeng LI,guojl@xidian.edu.cn,ID_CLXX@163.com

Journal Article

Improvement in the synthesis of 2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(Z)-methoxyiminoacetic acid 2-benzothiazolyl

GAO Shihao, SUN Chenghui, ZHAO Xinqi, GAO Changquan

Journal Article

Effective regeneration of thermally deactivated commercial V-W-Ti catalysts

Xuesong SHANG, Jianrong LI, Xiaowei YU, Jinsheng CHEN, Chi HE

Journal Article